Friday, 12th February 33rd Lorne Cancer Conference 2021

• To be provided - David Tuveson
• SMAD4 as a potential gatekeeper for genomic instability and mTOR-mediated tumourigenesis in oesophageal adenocarcinoma - Julia Milne
• Overcoming FOLFOX Resistance Through Effective Targeting of TP53 Independent Cell Cycle checkpoints in Metastatic Colorectal Cancer - Frederic Hollande
• Therapeutic effects of bazedoxifene in colon cancer  - Rhynelle Dmello
• Mechanisms and consequences of pancreatic cancer stromal evolution - Mara Sherman

• Unveiling cancer cell intrinsic and extrinsic mechanisms of small cell lung cancer metastasis - Kate Sutherland
• From mouse to man and back again in mesothelioma - Anna Nowak
• Targeting altered metabolism in the treatment of kras-mutant lung adenocarcinoma - Sarah A Best
• A novel methyltransferase-independent function of EZH2 in promoting melanoma progression via GTP production - Gamze Kuser Abali
• Deciphering Gastric Cancer Onset and Progression using Novel Mouse Models - Nicholas Barker
• TFAP-2β interacts with AR to determine the phenotype and growth of molecular apocrine breast cancer - Ebtihal Mustafa
• Using E-cadherin dynamics to predict cancer spread and response to anti-invasive therapies: Insights from intravital imaging - Daniel A Reed
• Understanding cancer immune evasion at the clonal level using DNA barcoding - Simon Junankar
• MicroRNA-based therapeutics for the treatment of high-risk neuroblastoma  - Holly Holliday
• Caspase-2 protects mutant-p53 cancer cells against ferroptosis - Swati Dawar
• Systematic analysis of chemo-immunotherapy combinations that lead to durable anti-tumour responses in murine mesothelioma - Nicola Principe
• An inflammatory, CD4+ T cell-driven tumour microenvironment sensitises tumours to cyclophosphamide chemotherapy - Caitlin M Tilsed
• Functional melanoma cell heterogeneity is regulated by MITF-dependent cell-matrix interactions - Nikolas K Haass
• Determining the essential functions of distinct pro-survival BCL-2 family members by using gene-swap mice - Kerstin Brinkmann

A reminder that flash talks are also available as E-posters.

2:00pm           Opening Remarks & Oncology Translational and Diagnostic Solutions of Present and Future

Presenter: Dr Bhavik Mehta (Senior Sales Manager - Oceania, BGI Health)

2:10pm           The Hudson-Monash Paediatric Brain Cancer Atlas Project 

                       Presenter: Dr Claire Sun (Bioinformatician, Hudson Institute)

2:25pm           Q&A (Live)

2:30pm           Large Field of View-Spatially Resolved Transcriptomics at Nanoscale Resolution

                       Presenter: Dr Xun Xu (CEO, BGI Group; Director, BGI Research)

2:45pm           MGI Single Cell Sequencing Solutions* 

                       Presenter: Dr Oliver Bonaccorso (Business & Channel Manager - ANZ, MGI Tech)

2:55pm           Q&A & Closing Remarks

* All Sequencers and Sequencing Reagents are not available in Germany, the US and Spain.